Customization: | Available |
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CAS No.: | 50-01-1 |
Formula: | CH5n3.Clh |
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Product Name: | Guanidine hydrochloride |
CAS: | 50-01-1 |
MF: | CH5N3.ClH |
MW: | 95.53 |
EINECS: | 200-002-3 |
Melting point | 180-185 °C(lit.) |
density | 1.18 g/mL at 25 °C(lit.) |
refractive index | n20/D 1.465 |
storage temp. | room temp |
solubility | H2O: 6 M, clear, colorless |
form | Crystals |
color | White to slightly yellow |
Odor | Odorless |
PH | 4.5-5.5 (100g/l, H2O, 20ºC) |
PH Range | 4.5 - 6.0 at 573 g/l at 25 °C |
Water Solubility | 2280 g/L (20 ºC) |
Sensitive | Hygroscopic |
Stability: | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
Application:Guanidine hydrochloride can be used as pharmaceuticals, pesticides, dyes and other organic synthesis intermediates. It can be used to synthesize 2-aminopyrimidine, 2-amino-6-methylpyrimidine, 2-amino-4,6-dimethylpyrimidine, and is used for the manufacture of sulfadiazine, sulfamethazine, sulfamethazine and other sulfa drugs. Intermediate. Guanidine hydrochloride (or guanidine nitrate) reacts with ethyl cyanoacetate to form 2,4-diamino-6-hydroxypyrimidine, which is used to synthesize the anti-anemia drug folic acid. It can also be used as an antistatic agent for synthetic fibers. Can also be used for protein denaturants. As a strong denaturant in experiments for extracting total cellular RNA[3]. The guanidine hydrochloride solution can dissolve the protein, leading to the destruction of the cell structure, the destruction of the secondary structure of the nucleoprotein, and the dissociation from the nucleic acid. In addition, the RNase can be inactivated by reducing agents such as guanidine hydrochloride.