Trifluoroacetic Acid CAS 76-05-1

• Customization: Available
• CAS No.: 407-25-0
• Formula: C2hf3o2
• Model NO.: 76-05-1
• EINECS: 206-982-9
• Carboxyl No.: Dicarboxylic Acid
• Appearance: Liquid
• Colour: Transparent
• Usage: 200kg
• Physic State: Liquid
• Transport Package: Drum
• Specification: 200kg
• Trademark: SENFEIDA
• Origin: Jiangsu
• HS Code: 29159080
• Production Capacity: 100tons/Month

Product Description

Product Name:	Trifluoroacetic acid
CAS:	76-05-1
MF:	C2HF3O2
MW:	114.02
EINECS:	200-929-3
Melting point	-15.4 °C (lit.)
Boiling point	72.4 °C (lit.)
density	1.489 g/mL at 20 °C (lit.)
vapor density	3.9 (vs air)
vapor pressure	97.5 mm Hg ( 20 °C)
refractive index	n20/D 1.3(lit.)
Fp	None
storage temp.	Store at +15°C to +25°C.
solubility	Miscible with ether, acetone, ethanol, benzene, hexane, and CCl<sub>4</sub>
form	Liquid
pka	-0.3(at 25ºC)
color	Colorless
Specific Gravity	1.480
Sensitive	Hygroscopic
Stability:	Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases.

Application:Stability: In the experiment of reverse phase chromatography for isolation of peptides and proteins, using trifluoroacetic acid (TFA) as the ion-pairing reagents is a common approach. Trifluoroacetic acid in the mobile phase can improve the peak shape and overcome the problem of the peak broadening and trailing issue through interaction with hydrophobic bonded phase and residual polar surface in a variety of models. Trifluoroacetic acid can bind to the positive charge and polar groups on the polypeptide in order to reduce the polar retention, and bring the polypeptide back to the hydrophobic inverting surface. With the same way, trifluoroacetate shield the residual polar surface in fixed phase. The behavior of TFA can be understood as it stuck in the phase surface of the reverse phase fixed phase, while having interaction with the polypeptide and column bed.
Trifluoroacetic acid has an advantage over other ion modifier due to that it is volatile and can be easily removed from the sample preparation. On the other hand, the maximum UV absorption peak of trifluoroacetic acid is less than 200 nm, and thus having very small interference on the detection of polypeptides at low wavelengths.
Varying the concentration of trifluoroacetic acid can slightly adjust the selectivity of polypeptide on reverse phase chromatography. The impact is very useful for optimizing separation conditions, increasing the amount of information contained in complex chromatography assay (such as the fingerprint of polypeptide).
Trifluoroacetic acid was added to the mobile phase in a general concentration of 0.1%. At this concentration, most of the reversed-phase column can produce good peak shape. In contrast, if the concentration of trifluoroacetic acid is significantly below this level, the peak broadening and tailing would become very obvious.
Trifluoroacetic acid has a good efficacy in the separation of proteins and other macromolecules. However, during the actual usage, we have a difficult time in controlling TFA concentrations because it is a volatile substance. If you configure it for a long time, it will be volatile causing change in the concentration. After completion of preparing it, it must be sealed for prevention of its evaporation.

Suzhou Senfeida Chemical Co., Ltd. is an environment-friendly high-tech enterprise integrating research and development, production and sales of fine chemical products. It has been working intensively on active diluents, UV curing resins, environmental solvents, organic intermediates and other types, and gradually formed three business segments of environmental chemicals, fine chemicals and new chemical materials. It is mainly used in many fields such as engineering plastics, green energy materials, printed circuit boards, semiconductors, information/communication, flat panel displays and optoelectronic industries.  

Based on the development concept of "characteristic, green and excellent", the company has developed more than 30 kinds of characteristic chemical products in six series by virtue of its technological innovation strength. Namely: environmental solvent series, special chemicals series, epoxy resin additive series. The products are widely used in environment-friendly high-end pesticides, coatings, pharmaceuticals, spices, building materials, new materials and other industries. The efficient scientific management team, strong product research and development strength, mature product quality control, and excellent after-sales service concept ensure the company's sustainable development and good competitiveness.
1 Q:Are you manufacturer?
A: Yes, we are a factory over 10 years and our products sales well on the market.

2 Q: What is your MOQ?
A: Our MOQ is at leasst 1 One package.

3 Q: What kind of package do you have?
A: We have various of packages to meet our customers,like Iron drums,plastic drums, IBC tanks, Flexitank, ISO TANK and bags etc.

4 Q :Which kind of payment terms do you accept?
A:We prefer TT, LC payment terms. Other payment terms are flexible to be further discussed.

5 Q: Can I get a sample?
A: Free samples are available, but buyers needs to pay freight.
But for high value item, should pay sample cost.

6 Q: How long does it take for me to get a sample?
A: It depends. Generally speaking, it is about 7-10 days.

7 Q: why is the quote offered different from the sticker price?
A: As we know, prices of chemicals are not fixed, they fluctuate with the markets.

8 Q:Can you give me a discount price?
A: Yes. It depends on your order qty.

9 Q: How about your delivery? When will my goods be shipped?
A: Prompt and reliable delivery by professional shipping lines.
About 3-5 days after prepayment is done.

10 Q: Is the quality of your products guaranteed? 
A: We have a professional R&D team, so every batch of our products is up to standard. We will have goods tested and provide COA before delivery for sure.