Customization: | Available |
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CAS No.: | 1122-58-3 |
Formula: | C7h10n2 |
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Product Name | 4-Dimethylaminopyridine |
CAS: | 1122-58-3 |
MF: | C7H10N2 |
MW: | 122.17 |
EINECS: | 214-353-5 |
Appearance: | Colorless Powder |
Melting point | 112 °C |
Boiling point | 162 °C |
Density | 0.906 g/mL at 25 °C |
Vapor pressure | 0.169 hPa at 20 °C |
Refractive index | n20/D 1.431 |
Fp | 110 °C |
Storage temp. | Store below +30°C. |
Solubility | methanol: 50 mg/mL, clear |
Pka | pKa (20°): 9.7 |
Packing | 200Kg/Drum |
Application:
4-Dimethylaminopyridine (Valaciclovir EP Impurity G; Valacyclovir USP Related Compound G) is a highly efficient catalyst for acylation reactions.
4-Dimethylaminopyridine is a versatile hypernucleophilic acylation catalyst, it is used to improve the yield, reduce the reaction time, improving relaxation process conditions.
Widely used in perfumes, dyes, pigments, pesticides, pharmaceuticals and polymer compounds and other fields. Also used as a catalyst for the synthesis of polyurethane, a curing agent and a blowing catalyst.
DMAP is a useful highly basic nucleophilic catalyst for a variety of reactions such as esterifications with anhydrides, the Baylis-Hillman reaction, hydrosilylations, tritylation, the Steglich rearrangement. In a wide variety of organic syntheses as a catalyst. A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3?5?phosphodiester linkage using an automated DNA synthesizer.